Identifying and addressing social determinants is becoming an essential part of healthcare. Despite their recognized impact on healthcare outcomes, actually identifying these determinants on both a patient- and population-level is difficult and often leaves us with an incomplete picture. Unstable housing is a major risk factor for many Hennepin Healthcare patients; this session will describe our journey to understand, identify and address this determinant with our patients. A novel approach to using population-level data to identify homelessness was our first step in eventually developing a multi-faceted indicator that is clinically meaningful. This approach is applicable to other healthcare organizations looking to take steps in identifying and addressing social determinants of health.