Sepsis and septic shock remain common causes of morbidity and mortality in children. This session will discuss how they investigated the use of electronic health record data to proactively identify potentially septic children. The approach used to define the early-detection pediatric sepsis (PS) algorithm was to combine the logical structure of a successful adult sepsis algorithm with clinical criteria consistent with the PS consensus definition of Goldstein et al. Multiple algorithm variations were retrospectively tested against a clinically-validated gold standard, and the one with the best overall performance under the constraint of early detection was implemented.
Recognize the process used to develop and evaluate the pediatric sepsis algorithm at Boston Children’s
Describe the range of operating characteristics of the pediatric sepsis algorithm based on different changes to the algorithm
Identify the strategy for inserting the algorithm into clinical workflows
Discuss the plans to iterate on the algorithm moving forward